Does Tight Glucose Control Enhance Brain Sensitivity to Low Glucose?

Does tight glucose control enhance brain sensitivity to low glucose?

Moving beyond tight glucose control to safe effective glucose control

The impressive benefits related to the use of tight glucose control by intensive insulin therapy have not been reproduced until now in multicenter large-scale prospective randomized trials. Although the reasons for these failures are not entirely clear, we suggest the use of a stepwise approach - Safe, Effective Glucose Control - that will essentially target an intermediate blood glucose level....

Does tight glucose control prevent myocardial injury and inflammation?

Hyperglycemia has been postulated to be cardiotoxic. We addressed the hypothesis that uncontrolled blood glucose induces myocardial damage in diabetic patients undergoing isolated coronary artery bypass graft surgery receiving continuous insulin infusion in the immediate postoperative period. Our primary aim was to assess the degree of tight glycemic control for each patient and to link the deg...

Tight Glucose Control Raised Mortality in ICU

S NOW

Tight glucose control: sweet or sour?

Introduction: The debate about the potential benefi ts of tight glucose control in intensive care patients has been ongoing since the exciting initial single-center study by Van den Berghe et al. [1], which demonstrated reduced mortality in patients managed according to a protocol aimed at maintaining blood glucose between 80 and 110 mg/dL compared with the then-standard goal of less than 215 m...